This article provides an in-depth look at severe primary immunodeficiency, detailing its causes, diagnostic procedures, and treatment options. It highlights the importance of early detection and effective management strategies to improve patient outcomes.

Understanding Severe Primary Immunodeficiency: Causes, Diagnosis, and Management

Severe primary immunodeficiency (PID) is a genetic condition that hampers the immune system's ability to fight infections. It occurs due to mutations in over 100 genes responsible for immune responses, leading to reduced antibody and white blood cell production. Affected children are vulnerable to frequent bacterial, fungal, parasitic, and viral infections. Early signs like recurrent illnesses, slow growth, and delayed wound healing are key indicators. Diagnosis involves blood tests for antibody levels and genetic analysis. Prevention focuses on sanitation, nutrition, and immunizations. Treatments include antibiotics, immunoglobulin replacement, and innovative options like stem cell and gene therapies.

Primary immunodeficiency

Genetic immune disorders

Infection prevention

Immunoglobulin therapy

Industry: Healthcare