This article explores the causes of medication-related liver inflammation, highlighting drugs, lifestyle factors, and chemical exposures that can lead to hepatitis. Recognizing these factors is vital for safe medication use and liver health maintenance.

Liver inflammation, or hepatitis, impairs the organ's essential functions. One often overlooked contributor is certain medications. Drug-induced hepatitis occurs when specific drugs harm the liver, but medication-related damage can also manifest as fatty liver or iron overload. The liver primarily processes food and drugs, including both over-the-counter and prescription medicines. Some individuals have slower liver detoxification, increasing vulnerability even to small doses. High doses or inappropriate drugs can also damage a healthy liver. Common culprits include acetaminophen, NSAIDs, steroids, antibiotics, and hormonal contraceptives. Factors like pre-existing liver conditions, alcohol intake, age, gender, multiple drugs, or herbal supplements can heighten risk. Exposure to chemicals like carbon tetrachloride or toxins from mushrooms can also lead to hepatitis. Always consult healthcare providers before starting medications to reduce liver damage risks.