Explore the comprehensive guide to Mississippi River cruises, detailing routes, best travel times, highlights, costs, and tips for an unforgettable journey through America's iconic waterway. Discover scenic landscapes, historic sites, and cultural experiences tailored to every traveler’s interest, whether exploring the upper or lower sections or combining both for a full adventure.

The Mississippi River stretches over 2,350 miles, originating at Lake Itasca in northern Minnesota and flowing south into the Gulf of Mexico. It sustains urban and agricultural water needs and is a cornerstone of American history. The river’s rich ecosystems support diverse wildlife, including migratory birds, and it functions as a major commercial waterway, moving approximately 175 million tons of cargo annually through 29 locks and dams. Its vast length and scenic vistas make it a perfect choice for extended river voyages.

The vibrant habitats along the Mississippi attract tourists, bird watchers, fishermen, and explorers. Themed cruises tailored to various interests provide unique experiences along the route.
When is the ideal time for a Mississippi River cruise? The cruise regions are divided into upper and lower sections. The Upper Mississippi includes cities like St. Louis and St. Paul, while the Lower features Memphis and New Orleans. The warmer Lower Mississippi can be cruised year-round except from mid-January to late February. The Upper section operates seasonally from June to October.

Most cruises last around 8 to 9 days, with shorter options also available. The Upper Mississippi cruises, mainly June through October, explore scenic towns and wildlife, with opportunities to see eagles and otters. The Lower Mississippi offers diverse itineraries featuring historic sites and local culture, available year-round. Some longer cruises combine both sections for journeys lasting 16 to 22 days.

Types of Mississippi River Cruises

Upper Mississippi Cruises: These seasonal voyages typically go between St. Louis and St. Paul, lasting up to nine days, with shorter options. Additional routes include trips from St. Louis to Ottawa and Memphis, as well as round trips originating from Red Wing, Minnesota, often incorporating the Ohio and Cumberland Rivers.

Lower Mississippi Cruises: Available throughout the year, these cruises generally run between Memphis and New Orleans, highlighting historic landmarks, local cuisine, jazz, and southern traditions.

Entire Mississippi River Cruises: Covering both sections, these extensive 16- to 22-day adventures run from New Orleans to St. Paul, offering an immersive experience of the river’s scenery and history.

Highlights of Upper Mississippi Cruises

This route from St. Louis to St. Paul features stunning natural scenery and lively small towns. Wildlife lovers may spot egrets, hawks, eagles, and otters. Navigating through around 20 locks, schedules may shift due to weather. Notable ports include Hannibal, Davenport, Dubuque, La Crosse, and Red Wing.

Highlights of Lower Mississippi Cruises

The Lower Mississippi offers a rich blend of history, culture, and entertainment. Visitors can tour historic plantations, enjoy southern cuisine and jazz, and explore iconic sites like Oak Alley, Nottoway Plantation, Baton Rouge, Natchez, Vicksburg, Helena, and Greenville, creating a memorable cultural and leisure experience.

Pricing for Mississippi River Cruises

Cost varies widely depending on itinerary, booking time, cruise duration, cabin class, and season. To find options suitable for your budget, search online or consult travel agents who provide comparison tools to help identify the best deals.

Choosing Your Ideal Cruise

Book early to secure preferred staterooms and discounts.

Consider adding local stays before or after the cruise for a more complete trip.

Be aware of all additional costs, amenities, and services for better value.

Select the vessel type—whether paddleboats, steamboats, or modern liners—that matches your experience style.

Review past traveler feedback to pick the best itinerary and cruise line to meet your preferences.

Note: Our blog offers helpful travel insights. While we provide guidance, please verify details and deals independently. We are not responsible for discrepancies or offers found elsewhere.