This article offers a detailed overview of colorectal cancer, covering its causes, stages, symptoms, and treatment options. Learn about the importance of early detection, genetic factors, and personalized care to improve outcomes. Stay informed and consult healthcare professionals for diagnosis and management.
Colorectal cancer, often called colon cancer, originates in the colon or rectum, key components of the digestive tract. It begins as benign growths known as adenomatous polyps on the intestinal lining. Without early detection, these polyps may transform into malignant tumors over time. Annually, roughly 1 in every 21 men and 1 in each 23 women receive a diagnosis of colon cancer, ranking it among the top causes of death—second for women and third for men. Medical advancements have contributed to a decline in new cases.
The disease develops through four stages: initial, localized, lymph node involvement, and distant spread. Its primary causes involve genetic mutations—either inherited or acquired—that interfere with normal cell regulation. Conditions like Lynch syndrome and mutations in the APC gene are common genetic factors. Symptoms such as altered bowel habits, rectal bleeding, unexplained weight loss, and abdominal discomfort should prompt medical evaluation. Treatment modalities include chemotherapy, tumor removal, and surgical intervention, tailored to the disease stage.
Initial stage: Confined within colon layers
Early progression: Extends beyond inner layers but not into the rectum
Intermediate stage: Involves nearby lymph nodes
Advanced stage: Metastasizes to distant organs
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